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Timeline

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  • The Story of Alfred Mann
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  • Timeline
  • 2011 RFM Clinical Trials RFM Clinical Trials
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    2011 – Clinical trials with the RFM are planned for patients suffering from dysphagia as a result of head and neck cancer and for patients with upper limb hemiplegia as a result of traumatic brain injury

    RFM Clinical Trials

  • 2011 Infusion Systems Infusion Systems
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    2011 – Clinical trials with the Infusion Systems drug delivery system are launched for patients with back pain

    Infusion Systems

  • 2010 Infusion Systems, Inc. Infusion Systems, Inc.
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    2010 – Infusion Systems, Inc. and its implantable drug delivery technology is acquired by AMF

    Infusion Systems, Inc.

  • 2008-2009 RFM Clinical Trials RFM Clinical Trials
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    2008-2009 – AMF pursues clinical trials with the RFM on lower limb applications for patients with stroke and spinal cord injuries

    RFM Clinical Trials

  • 2004 Bioness, Inc Bioness, Inc
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    2004 – Bioness, Inc. is established and granted a license to use technology for rehabilitation applications.

    Bioness, Inc

  • 2003-2005 RFM Clinical Trials RFM Clinical Trials
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    2003-2005 – clinical trials with the RF microstimulator (RFM) device are conducted in applications relating to obstructive sleep apnea, shoulder subluxation, and post-stroke upper limb hemiplegia

    RFM Clinical Trials

  • 2003 IMES IMES
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    2003 – AMF, Illinois Institute of Technology and the Rehabilitation Institute of Chicago form a partnership to develop an Implantable MyoElectric Sensor (IMES) system that could be used to control prosthetic limbs

    IMES

  • 2001 BION® Developed BION® Developed
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    2001 – AMF licenses microstimulator technology to Advanced Bionics for certain medical applications. Advanced Bionics develops a battery-powered microstimulator device called BION®, which is used in clinical trials for urinary incontinence. Boston Scientific later obtains this license and develops a BION® application to treat migraine headache

    BION® Developed

  • 1999 BPM Implant BPM Implant
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    1999 – AMF begins development of a battery-powered microstimulator (BPM) implant, which will have a rechargeable battery, high-speed two-way telemetry, and sensing capabilities

    BPM Implant

  • 1996 MRG Formed MRG Formed
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    1996 – Medical Research Group (MRG) is formed to work on the long-term glucose sensor, one of AMF’s founding projects

    MRG Formed

  • 1993 Advanced Bionics Formed Advanced Bionics Formed
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    1993 – Advanced Bionics is formed and receives the license to manufacture and distribute the Clarion® Cochlear Implant

    Advanced Bionics Formed

  • 1991 Microstimulator Microstimulator
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    1991 – AMF and its partners deliver the first prototype of the implantable microstimulator device, which is powered and controlled using radio frequency (RF) and is encased in a glass capsule. A subsequent iteration of the RF-powered microstimulator (RFM) employs a stronger hermetic casing made of ceramic

    Microstimulator

  • 1989 Neurostimulator Neurostimulator
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    1989 – In collaboration with the Illinois Institute of Technology (IIT) and Queens University in Canada, AMF begins development of a miniature implantable neurostimulator device. AMF works on the hermetically sealed case, IIT on circuitry, and Queens on communication protocol

    Neurostimulator

  • 1986 Clarion® Cochlear Implant Clarion® Cochlear Implant
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    1986 – Together with the University of California San Francisco and The Research Triangle Institute, AMF works on the enabling technology for what will become the Clarion® Cochlear Implant

    Clarion® Cochlear Implant

  • 1985 AMF Founded AMF Founded
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    1985 – The Alfred Mann Foundation is founded with a gift from Alfred Mann and the sale of Siemens stock

    AMF Founded

RFM Clinical Trials

RFM Clinical Trials

2011 – Clinical trials with the RFM are planned for patients suffering from dysphagia as a result of head and neck cancer and for patients with upper limb hemiplegia as a result of traumatic brain injury

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