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2011
RFM Clinical Trials
2011 – Clinical trials with the RFM are planned for patients suffering from dysphagia as a result of head and neck cancer and for patients with upper limb hemiplegia as a result of traumatic brain injury
RFM Clinical Trials
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2011
Infusion Systems
2011 – Clinical trials with the Infusion Systems drug delivery system are launched for patients with back pain
Infusion Systems
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2010
Infusion Systems, Inc.
2010 – Infusion Systems, Inc. and its implantable drug delivery technology is acquired by AMF
Infusion Systems, Inc.
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2008-2009
RFM Clinical Trials
2008-2009 – AMF pursues clinical trials with the RFM on lower limb applications for patients with stroke and spinal cord injuries
RFM Clinical Trials
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2004
Bioness, Inc
2004 – Bioness, Inc. is established and granted a license to use technology for rehabilitation applications.
Bioness, Inc
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2003-2005
RFM Clinical Trials
2003-2005 – clinical trials with the RF microstimulator (RFM) device are conducted in applications relating to obstructive sleep apnea, shoulder subluxation, and post-stroke upper limb hemiplegia
RFM Clinical Trials
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2003
IMES
2003 – AMF, Illinois Institute of Technology and the Rehabilitation Institute of Chicago form a partnership to develop an Implantable MyoElectric Sensor (IMES) system that could be used to control prosthetic limbs
IMES
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2001
BION® Developed
2001 – AMF licenses microstimulator technology to Advanced Bionics for certain medical applications. Advanced Bionics develops a battery-powered microstimulator device called BION®, which is used in clinical trials for urinary incontinence. Boston Scientific later obtains this license and develops a BION® application to treat migraine headache
BION® Developed
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1999
BPM Implant
1999 – AMF begins development of a battery-powered microstimulator (BPM) implant, which will have a rechargeable battery, high-speed two-way telemetry, and sensing capabilities
BPM Implant
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1996
MRG Formed
1996 – Medical Research Group (MRG) is formed to work on the long-term glucose sensor, one of AMF’s founding projects
MRG Formed
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1993
Advanced Bionics Formed
1993 – Advanced Bionics is formed and receives the license to manufacture and distribute the Clarion® Cochlear Implant
Advanced Bionics Formed
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1991
Microstimulator
1991 – AMF and its partners deliver the first prototype of the implantable microstimulator device, which is powered and controlled using radio frequency (RF) and is encased in a glass capsule. A subsequent iteration of the RF-powered microstimulator (RFM) employs a stronger hermetic casing made of ceramic
Microstimulator
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1989
Neurostimulator
1989 – In collaboration with the Illinois Institute of Technology (IIT) and Queens University in Canada, AMF begins development of a miniature implantable neurostimulator device. AMF works on the hermetically sealed case, IIT on circuitry, and Queens on communication protocol
Neurostimulator
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1986
Clarion® Cochlear Implant
1986 – Together with the University of California San Francisco and The Research Triangle Institute, AMF works on the enabling technology for what will become the Clarion® Cochlear Implant
Clarion® Cochlear Implant
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1985
AMF Founded
1985 – The Alfred Mann Foundation is founded with a gift from Alfred Mann and the sale of Siemens stock
AMF Founded
RFM Clinical Trials
2011 – Clinical trials with the RFM are planned for patients suffering from dysphagia as a result of head and neck cancer and for patients with upper limb hemiplegia as a result of traumatic brain injury





